Evaluation of the Quantitative Cytological Changes in the Epithelium of the Uterine Cervix

The cytological investigation is a subjective method which does not allow to determine accurately the morphological changes of the epithelium cells, therefore additional diagnostic methods must be used. Such a method is the Quantitative DNA Analysis. We used the obtained results for statistical processing in order to deternime whether there is a significant difference between the cell populations with different degrees of dysplasia and in cases of carcinoma of the uterine cervix. No such differences were registered between the diploid cells in phases of DNA presynthesis and synthesis. Significant difference was calculated when we compared aneuploid cells. This means that cell populations with different degrees of dysplasia can be distinguished by the aneuploid cells in the smear.